Associate Director, Cell-Based Assay Development/Screening

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The Company 

Sonata Therapeutics is a new, Boston-based Flagship Pioneering company revolutionizing the world’s understanding of the cellular microenvironment and its importance to human biology and disease. Our product-platform creates drugs based on a systematic, comprehensive characterization of the microenvironment in diseases with high unmet medical need. Through our pioneering science, we identify new targets for therapeutics that induce the release of a programmed diversity of signals with the potential for significant patient impact. Our employees are exceptionally passionate, accountable, collaborative, and innovative.

Sonata Therapeutics was founded by Flagship Pioneering, an organization dedicated to the origination and development of first-in-category life sciences companies.  Since 2000, Flagship has originated and fostered the development of nearly 100 scientific ventures resulting in $20+ billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents.   

The Position:  

Due to the expansion of our R&D capabilities, we are currently on the hunt for a creative Associate Director/Director, Cell-Based Assay Development/Screening, to build and develop a world-class team of scientists to advance and expand Sonata’s platform technology. 

As the Associate Director/Director, you will work across multiple therapeutic areas and projects, providing scientific advisement to develop and deploy cellular assays to identify and characterize the next generation of genetic therapeutics at Sonata. You will work cross-functionally to develop creative and innovative strategies and approaches to screen Sonata’s proprietary libraries across an array of in vitro, disease-relevant cell-based assays.  You will lead a small team of biologists, assigning projects, managing performance, and providing training to new and existing team members.

Sonata Therapeutics offers the challenge and opportunity to work at an early-stage, big concept biotechnology company. You will be essential to expanding our R&D project portfolio across new and existing therapeutic areas.

 

You will be making a significant impact by…

  • Directly oversee a small group of scientists executing cell-based assays aimed at discovering Sonata's next-generation therapeutics, including performance management and training of new and existing staff.
  • Supervising the design, execution, interpretation, and communication of experiments to identify novel targets across our therapeutic platform, with an ability to integrate in vitro and in vivo discovery strategies
  • Develop screening assays in a variety of cell-based formats, including co-culture culture systems
  • Design and implement strategies to use automation capabilities to increase throughput and robustness of assays
  • Leverage a wide variety of high-performance instrumentation to achieve discovery platform objectives
  • Proactively engaging with colleagues from diverse functional areas as well as developing external collaborations with academic and biotechnology partners to develop and integrate enabling technology to identify novel targets

 

As an excellent candidate, you will possess...

  • Ph.D. in chemistry, biology, or biochemistry and 5+ years’ experience in Pharma/biotech setting with phenotypic screening is required. Experience managing a team is preferred
  • Experience with cell-based assay development is a must! Experience with immune-assay development would be a plus but not required.
  • Demonstrated competence with a wide variety of screening techniques
  • Experience working with diverse scientific teams required.
  • Experience with prioritization of multiple projects
  • Experience with automation, high performance instrumentation, and/or high content imaging is preferred
  • Strong analytical and problem-solving skills.
  • Excellent communicator with the ability to convey complex messages to many audiences.
  • Confident, execution-focused, team-oriented.

 

Sonata Therapeutics and Flagship Pioneering are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or veteran status.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.