The Associate Director/Director of Translation Research will report to the Senior Vice President of Biology and will be responsible for driving the in vivo and translational efforts in a fast-paced small molecule discovery research team. You will use your scientific and organizational leadership to advance small molecule drug discovery projects from program initiation to selection of development candidates and regulatory submission. Responsibilities include driving scientific research to identify, evaluate, and characterize disease relevant in vivo assays and other fluid/tissue biomarkers to provide efficacy and pharmacodynamic endpoints in preclinical and clinical settings.

What You'll Do:

• Provide strategic, scientific, and managerial leadership to drive the in vivo and translational scientific efforts
• Develop in vivo and biochemical assays to evaluate efficacy, PK/PD relationships, and novel biomarkers to characterize molecules for potential therapeutic activity and efficacy
• Communicate, collaborate, and coordinate effectively with cross-functional teams
• Prepare, review and deliver high quality scientific presentations for internal/external use.
• Serve as translational and in vivo lead (directly and/or indirectly) for multidisciplinary drug discovery project teams in a fast-paced, results-driven biotech environment

What You'll Bring:

• Ph.D. in Neurobiology/Neurophysiology/Neuropharmacology or similar with 10+ years of drug discovery experience in the biotech/pharmaceutical industry
• A strong track record of success in delivering clinical candidates
• Broad background in all aspects of drug discovery, with working knowledge of in vivo pharmacology, biomarker identification and translational research, ADME/PK, and in vitro pharmacology
• Extensive experience of managing and delivering high quality studies through CROs and academic collaborators; demonstrated ability to negotiate contracts, develop study protocols and on-time delivery of study reports supporting development candidate nomination and regulatory submissions
• Strong organizational, interpersonal, communication, and managerial skills that motivate and inspire others to achieve corporate scientific objectives
• A passion and sense of urgency for delivering important new therapies to patients is essential

What We’ll Offer You:

• Comprehensive, competitive healthcare (PPO) and dental coverage through Blue Cross Blue Shield, vision coverage through VSP, family leave, paid time off, 401k retirement plan, disability and life insurance, and commuter benefits.
• A dynamic early-stage work environment and highly interdisciplinary, talented, and collaborative team.
• Participation in projects that could redefine treatment of common illnesses.
• Professional growth opportunities through mentoring, training, immersion in cross-functional projects, and opportunities to learn and try new things.
• Daily on-site snacks, all the coffee you can drink, and weekly catered lunches.

Who We Are:

At Vesalius Therapeutics, we believe it is time to re-think and redefine how we treat common illnesses. Founded by Flagship Pioneering, which has originated over 40+ breakthrough companies, including Moderna, Rubius, and Editas Therapeutics, we are building a company capable of doing it.

Vesalius combines the power of artificial intelligence and machine learning, genetics, bioanalytics, and proprietary experimental models to bring a fresh approach to treating common, complex illnesses. Join us in advancing human-driven science with the power to benefit the lives of patients.