Company Summary:

Generate Biomedicines, Inc. is a Flagship backed, privately-held biotechnology company on a mission to reimagine the drug discovery process to one of dynamic, data-driven generation. We pursue this audacious vision because we believe in the unique and revolutionary power of generative biology to radically transform the lives of billions, with an outsized opportunity for patients in need. Generate will be successful by constantly turning innovative ideas into methods, technologies, and products that solve some of the most difficult challenges with developing medicines. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us!

Generate was founded by Flagship Pioneering. Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has applied a unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $34 billion in aggregate value. The current Flagship ecosystem comprises 41 transformative companies, including: Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Foghorn Therapeutics, Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS). 

Job description

Generate Biomedicines is seeking a motivated scientist to lead the molecular biology activities supporting high-throughput protein production. The successful candidate will join a talented team of researchers in executing high-throughput cloning methods on automated liquid handling robots. Work across multiple protein modalities, including antibodies and enzymes. Collaborate with groups across Generate including Machine Learning, Informatics, Computational Biology, Automation Working Group, and other teams within Protein Sciences. 

Responsibilities

• Lead a team through planning and execution of high-throughput cloning workstreams
• Oversee planning, execution, and tracking of cloning workflows using our world class informatics and database tools
• Curate structured data and perform database queries
• Conduct quality control assessments of DNA samples before hand off for mammalian transfection, including use of MiSeq and NanoPore technologies
• Perform batch data analysis from Sanger and NGS outputs
• Maintain excellent quality control standards and archival practices

Required skills

• PhD with 0 to 5 years experience. BS/MS degree in Molecular Biology, Cell Biology or related field will also be considered. 
• 1-5 years of experience working in drug discovery for BS/MS candidates
• Expertise in modern cloning techniques (Golden Gate, Gibson, etc) 
• Expertise in DNA quality control, bulk sequence analysis, and sequencing technologies
• Experience with scripting and programming (Python, R, SQLite, C++) 
• Experience working with liquid handling robots is strongly preferred
• Experience working with antibodies and knowledge of antibody structure is strongly preferred

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.