Senior Research Associate, Analytical Development - ELISA
See more jobs from Flagship Pioneeringover 2 years old
Company Summary:
Tessera Therapeutics is pioneering Gene Writing™— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.
Position Summary:
The Senior Research Associate will be responsible for development and execution of ELISAs to support all modalities. We are searching for a driven, enthusiastic and self-motivated individual who is comfortable multitasking and working independently on various aspects of the platform. This individual will join a dynamic, rapidly growing, and highly collaborative team.
Key Responsibilities:
The successful candidate will work both independently and as part of a collaborative team to:
- Develop, optimize, qualify, validate, and troubleshoot analytical methods as required
- Focus on protein binding assays such as ELISAs to support product and process development across modalities for IND-enabling studies
- Contribute to an ELISA center of excellence with experience in various binding assays, instrumentation, and software while
- Organize and maintain laboratory space, inventory, and supplies
- Design, preform and document assays in a repeatable and efficient manner
- Write and review methods and documentation including protocols, SOPs, reporting of testing, analytical method development and qualification studies.
- Communicate effectively with team members
- Develop and qualify controls/standards, and perform regular data trending
- Collaborate with Process Development to enhance product and process understanding using fit-for-purpose, stage-appropriate analytical assay development
- Mentor junior analysts to ensure timely completion of assignments with full data integrity.
Basic Qualifications:
- BS/MS with 6-8 years of industry experience
- Self-motivated, enthusiastic, and detail-oriented with a positive and innovative attitude
- Strong organizational, communicative, and analytical skillsetwith previous independent analytical development experience
- Extensive industry experience with ELISA required with biochemistry/protein chemistry knowledge preferred
- Ability to use Excel and working knowledge and understanding of statistical data analysis is required
- Proficient experience in associated analytical techniques such as Western Blotting, HPLC, flow cytometry, and cell-based assays is a preferred
- Good leadership skills, strong desire to both learn and mentor, and ability to contribute at a high level
More About Flagship Pioneering
Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has, through its Flagship Labs unit, applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $50B in aggregate value. To date, Flagship has deployed over $2.2B in capital toward the founding and growth of its pioneering companies alongside more than $18B of follow-on investments from other institutions. The current Flagship ecosystem comprises 41 transformative companies, including Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Foghorn Therapeutics (NASDAQ: FHTX), Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Sigilon Therapeutics (NASDAQ: SGTX).