Senior Scientist/Principal Scientist, Medicinal Chemistry

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As the Senior Scientist/Principal Scientist of Medicinal Chemistry at Vesalius Therapeutics, you will report to the Senior Vice President of Drug Discovery and will be responsible for driving medicinal chemistry efforts in a fast-paced small molecule discovery research team. You will use your scientific and organizational leadership to advance small molecule drug discovery projects from program initiation to selection of development candidates.

What You'll Do:

  • Discover and advance novel small molecule drugs into clinical development
  • Provide strategic, scientific, and managerial leadership to medicinal chemistry team
  • Define, implement, and execute on medicinal chemistry strategies
  • Serve as chemistry lead (directly and/or indirectly) for discovery programs
  • Collaborate with IP team to create and execute strategy to establish, protect and expand intellectual property
  • Plan for and prioritize internal and external medicinal chemistry resources to achieve project goals
  • Communicate, collaborate, and coordinate effectively with cross-functional teams
  • Prepare, review and deliver high quality scientific presentations for internal/external use
  • Lead multidisciplinary drug discovery project teams in a fast-paced, results-driven biotech environment

What You'll Bring:

  • Ph.D. in Organic Chemistry or Medicinal Chemistry with 5+ years of drug discovery experience in the biotech/pharmaceutical industry
  • A strong track record of success in delivering clinical candidates
  • Broad background in all aspects of drug discovery, with working knowledge of structural biology, ADME/PK, in vitro assays, and in vivo pharmacology
  • Experience in managing chemistry CRO activities and academic collaborators; demonstrated ability to negotiate contracts, develop study protocols and on-time delivery of study reports supporting development candidate nomination and regulatory submissions
  • Strong organizational, interpersonal, communication, and managerial skills that motivate and inspire others to achieve corporate scientific objectives
  • A passion and sense of urgency for delivering important new therapies to patients is essential

What We’ll Offer You:

  • Comprehensive, competitive healthcare (PPO) and dental coverage through Blue Cross Blue Shield, vision coverage through VSP, family leave, paid time off, 401k retirement plan, disability and life insurance, and commuter benefits.
  • A dynamic early-stage work environment and highly interdisciplinary, talented, and collaborative team.
  • Participation in projects that could redefine treatment of common illnesses.
  • Professional growth opportunities through mentoring, training, immersion in cross-functional projects, and opportunities to learn and try new things.
  • Daily on-site snacks, cold brew coffee, and Bevi, as well as weekly catered lunches.

Who We Are

At Vesalius Therapeutics, we believe it is time to re-think and redefine how we treat common illnesses. Founded by Flagship Pioneering, which has originated over 40+ breakthrough companies, including Moderna, Rubius, and Editas Therapeutics, we are building a company capable of doing it.

Vesalius combines the power of artificial intelligence and machine learning, genetics, bioanalytics, and proprietary experimental models to bring a fresh approach to treating common, complex illnesses. Join us in advancing human-driven science with the power to benefit the lives of patients.

 
Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
 
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.