What if... We could harness the power of Flagship’s scientific platforms and create novel treatment options that benefit more patients, sooner?

Pioneering Medicines, an initiative of Flagship Pioneering, is building a world-class biopharmaceutical R&D capability focused on conceiving and developing life-changing treatments for patients by harnessing the power of Flagship's scientific platforms and applying those innovative approaches to serious diseases with unmet medical need. Unique to Pioneering Medicines’ approach is the opportunity to combine platforms to create truly novel and potentially transformative treatments. 

About Flagship Pioneering:

Flagship Pioneering conceives, creates, resources, and develops first-in-category life science platform companies to transform human health and sustainability. Since its founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures, resulting in over $34 billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents.  

Position Summary:

We are seeking a Senior Research Associate Contractor to support assay development, in vitro pharmacology and ex vivo analyses across multiple therapeutic areas, including but not limited to metabolic/cardiovascular disease, oncology and inflammation. This individual will be responsible for independently designing, optimizing, and performing cell-based assays to support the discovery and development of novel therapeutics across a variety of modalities. This individual will also collaborate closely with in vivo pharmacology, translational science, and nonclinical groups to help execute on company strategy.

Our 3rd party agency will be hiring for this position for a 6 month or more contract.

Key Responsibilities:

• Support the screening, characterization, and mechanism of action studies for drug candidates of various modalities, including small molecules, biologics and nucleic acids
• Independently design, optimize and execute medium-to-high throughput cell-based assays to support drug discovery/development programs
• Analyze scientific data and clearly communicate summarized data to internal Pioneering Medicines team members and other key stakeholders
• Accurately record detailed documentation of experimental results via ELN (Electronic Lab Notebook)/Benchling

Basic Requirements:

• BS with 3-5 years of experience or MSc with 2+ years of experience in Biology or related discipline in an academic or industrial research setting (preferred)
• Expertise in cell culture of immortalized cell lines, primary airway epithelial cells and complex cell culture models
• Experience in cell-based assay development to evaluate the pharmacology of potential therapeutic agents (e.g., small molecules, biologics, nucleic acids)
• Demonstrated ability to develop and execute various in vitro and ex vivo assays (e.g., ELISA, flow cytometry, MSD, high content image analysis, Western blotting, immunocytochemistry, qPCR/ddPCR)
• Proficiency in scientific software (e.g., Excel, GraphPad Prism, FlowJo)
• Ability to operate as part of a team and work with colleagues across the organization to advance projects at all stages.