About Inzen: 

Inzen Therapeutics is a privately held, early-stage biotechnology company exploring ThanokineTM Biology as a surprising and vital driver of disease.  While the ability of living cells to respond to messages from other living cells is a well-established concept, Inzen has identified that living cells also respond to messages released by cells as they undergo turnover and die. We call these messages Thanokines, and the way a cell undergoes turnover dramatically alters the released Thanokines. Thanokines can elicit a broad array of responses in living cells, and we have demonstrated that ThanokinesTM plays a previously unrecognized role in the pathogenesis of many important diseases. Our mission is to pioneer a novel category of drugs based on manipulating ThanokineTM Biology to treat cancer, immune and fibrotic diseases, and regenerative processes.   

Inzen Therapeutics was founded by Flagship Pioneering, an organization dedicated to the origination and development of first-in-category life sciences companies.  Since 2000, Flagship has originated and fostered nearly 100 scientific ventures resulting in $20+ billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents.       

The Position:    

Due to the expansion of our R&D capabilities, we are currently on the hunt for a skilled Scientist to join our new In Vivo Pharmacology Team. You will play a vital role in building out our internal capabilities. You will design and execute critical in vivo studies in our fast-paced and interactive research environment across all therapeutic areas, including oncology and fibrosis.  

Inzen Therapeutics offers the challenge and opportunity to work at an early-stage, big concept biotechnology company. Your efforts will have a lasting impact on our development programs leading to future success in the clinic.    

Crucial Responsibilities:    

• Design, execute, analyze and interpret decision-making in vivo pharmacology experiments supporting Thanokine Biology projects across the Inzen portfolio (e.g., cancer, immune and fibrotic diseases, and regenerative processes).  
• Perform in-house studies as well as manage studies outsourced to CROs.  
• Participation in hands-on in vivo pharmacology work is a key part of the role.  
• Present findings clearly and concisely to cross-functional project teams. 

As a Strong candidate, you will possess:    

• Bachelor’s Degree in Immunology, Pharmacology, Cancer biology, or other biological science with 6+ years of relevant experience or equivalent combination of education and experience. 2 years of experience working in a biotech or pharmaceutical company is required.  
• Must have experience in experience in evaluating therapeutic candidates in vivo models 

• Must have experience carrying out in-life procedures for rodent cancer models.  
• Required technical expertise includes administering treatments to rodents (PO, IV, IP, SC, IT dosing); preparation and formulation of compounds for dosing; blood collection by microsampling (tail puncture, facial vein); Rodent tissue collection, blood collection by cardiac puncture, and necropsy 
• Preferred technical skills and experience include experience in working with fibrosis animal models or PDX models; cell culture and preparation of tumor cells for implantation; experience with rodent survival surgery procedures; hepatectomy, bile duct ligation, portal vein or splenic artery injection; bronchoalveolar lavage collection 
• Experience with tumor measurements, data collection, and graphing software (e.g., Prism)  
• Must possess the ability to adapt to and leverage your superior problem-solving skills in a face-paced environment and the flexibility to change priorities as needed.     
• Superior verbal/presentation communications skills are required to persuade cross-functional teams to make decisions based on sound scientific expertise.     

Inzen Therapeutics and Flagship Pioneering are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or veteran status.   

 Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.