The Company

FL94 Inc., is a privately held, early-stage biotechnology company pioneering Protein Editing. FL94’s goal is industry-changing expansion of our ability to cure diseases by precisely hitting the many validated disease targets that traditional chemistry cannot touch. FL94’s core platform combines innovative small molecule chemistry with generative AI.

FL94 was founded by Flagship Pioneering, with the support of its leadership, Noubar Afeyan, Ruppert Vessey and Geoffrey von Maltzahn. Flagship brings the courage, vision, and resources to guide FL94 from platform validation to patient impact. As a Flagship company we have access to the Flagship ecosystem, including capital and industry networks, senior scientific and business expertise and core shared services.

We are seeking collaborative, relentless problem solvers that share our passion for impact to join us! 

The Position

You will be responsible for enabling investment decisions across Program Portfolio and Platform capabilities and developing the Portfolio Strategy for FL 94. This position will be critical in setting the overall FL94 investment strategy, portfolio priorities and long-term vision. Additionally, this individual will combine seasoned leadership with understanding of medical value along the whole R&D value chain, risk evaluation and management and scientific acumen. 

The successful candidate will be a practitioner of Strategic and Corporate Finance and have deep familiarity with (i) asset and portfolio evaluation, (ii) stage gates and progression criteria along the R&D value chain.

This is a full-time, on-site (i.e., not remote) position in Cambridge, Massachusetts. The position requires an advanced degree (MD or PhD).

Responsibilities

Portfolio  Management:

• Lead corporate-level investment decisions analytics
  • Strategic Finance: frame and quantify trade-offs among investment decisions involving programs and platform to enable Leadership Team-level investment allocation
• Build a Portfolio strategy to maximize portfolio value
  • Collaborate with scientific and corporate functions develop a coherent strategic, operational, and financial view of FL94’s Platform and Program Portfolio
  • Enable LT-level strategic decision-making
• Lead Portfolio Analytics:
  • Programs value and risk assessment - from proof-of-concept to commercial
  • Portfolio Ad Boards covering different Programs or TAs, as needed
  • Portfolio workshops with senior leadership to enable go/no-go decisions and resource allocation
• Lead proactive program risk mitigation
  • Collaborate with Functions and Program Teams to identify major failure modes and develop mitigation
  • Set up risk monitoring and reporting processes and infrastructure

Competitive Insights:

• Maintain an up-to-date view on the competitive landscape
• Derive implications for strategy and resources allocation
• Lead outsourced Competitive Insights efforts

Leadership & Communication:

• Lead Program & Portfolio management meetings
• Develop insights and analytics for Portfolio meetings and Investor, and Board interactions as needed

Personal Qualities, Skills & Expertise:

• Values-driven leader
• Solution-oriented, first-principles problem solver
• Versatile learner
• Excellent communicator who interacts with others with high level of transparency and respect
• Multi-tasker
• Demonstrated ability to lead cross-functional teams and strategic corporate initiatives.
• Ability to meld science, market insights, and competitive intelligence into compelling, value-creating strategies.
• Strong project management skills, ability to ensure effective/efficient decision-making
• Strong interpersonal skills and ability to perform under pressure to meet challenging deadlines.
• Ability to synthesize and present to senior executives, including Board, a complex set of facts (i.e. scientific, clinical, financial, and market information) to facilitate the decision-making process.
• Outstanding presentation and communication skills

Qualifications:

• 10+ years of industry experience
• MD and/or PhD
• Track record in Asset evaluation, Strategic and Corporate Finance
• Exposure to R&D value chain across major TAs

About Flagship

Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. 

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.